Reaction Monitoring

Designed to provide fundamental support and extraction of spectroscopic and chemical kinetic concentration from arrayed NMR datasets.

Collect your NMR spectra at regular intervals through the course of a chemical reaction.

Mnova RM: 45-day FREE trial

product_icon_download 1. Download

RM is a plugin integrated in MnovaNo extra installer is required.

product_icon_install 2. Installation

Open Mnova and go to ‘Help/Get-Install Licenses’. Select ‘Evaluate’.

product_icon_license 3. License

Fill in the form to receive your trial license via e-mail.

RM

Specifications

Mnova makes the analysis of RM data simple, providing a sophisticated suite of software solutions to what can be somewhat tricky data to analyse.

  • Complex reactions and large data files can be analyzed very quickly and easily.
  • Provides a versatile suite of data import tools. Metadata is extracted, for example to automatically build a time axis.
  • Excellent spectral processing capabilities:
    • Autophase
    • Peak alignment
  • Automated data analysis as the data are produced by the spectrometer.
  • Use the built-in tools to construct a curve of concentration vs time – the correct way to analyse reaction kinetics.

RM

Features

Real-Time Reaction Monitoring

Fully unassisted reaction monitoring analysis and report of your datasets. All your kinetic parameters and reaction endpoints are determined as soon as data are acquired and found in a predefined location folder.

Each new spectrum is added to the existing analysis, curve fitting parameters are updated, and component concentration can be tracked, so that the analysis is conducted without user intervention.

The combination of the Real Time RM with Mnova’s scripting capabilities can allow you to fully automate currently time consuming workflows.

A simple graphical user interface will guide you in the process of setting up your Real-time RM, so that analysis set up takes a couple of minutes and requires no specific expertise.

Kinetic curve generation

Mnova RM provides an environment to easily work on reaction data in the usual concentration v time way.

Mnova allows you to separate the raw data into separate kinetic analyses. The time at which each spectrum was acquired is read and used to build the final x-axis in the kinetic plot.

Mnova provides a host of powerful data processing tools to deal with poor baseline, changing phase, strong interfering (solvent) signals. Difficult peak area determination can be addressed using GSD. The spectral array can be further curated by individual reprocessing.

Finally, the kinetic curve data points can be fit to a specified mathematical function to determine the kinetic parameters. An exponential fitting function is powerful and fast.

Academic, Government & Industrial

Markets

  • Fine chemical production
  • Oil and gas industry
  • Pharmaceutical drug development and production
  • Process chemistry, PAT and QbD among others
Harvard University