State of the art automatic analysis tool for ligand screening NMR data. It offers flexibility for the analysis and reporting of results.
The objective of this module is to allow the simple and efficient analysis of Ligand Binding Screening experiments (WaterLOGSY, STD, T1rho, CPMG) –1H, 19F.
Data review and spectrum comparison reduced to a ‘human reviewed’ automated process.
Mnova Screen: 45-day FREE trial
1. Download
Once you install Mnova, download this installer to your hard drive (below).
2. Installation
Open Mnova and go to ‘Help/Get-Install Licenses’. Select ‘Evaluate’.
3. License
Fill in the form to receive your trial license via e-mail.
Mnova Screen is an advanced plugin. You need Mnova to use Screen plugin.
Help & Resources
Resources
Articles
SCREEN
Highlights
The results viewer enables quick and efficient inspections.
Academic, Government & Industrial
Markets
- Structural biology, biophysics and NMR groups in pharmaceutical companies.
- Target based drug discovery and NMR groups in academic and research institutions.
- CRO’s and service providers for target based lead detection and lead optimization.
Success Stories
Case Studies
A successful collaboration with Novartis on automated analysis of ligand-observed 1H-19F NMR binding data for fragment based lead generation
Several groups in Novartis use NMR binding assays to find and validate hits during the early stages of drug discovery. They use ligand-observed NMR experiments such as STD, T1ρ, and CPMG to identify library compounds that interact with a target protein. Until a few years ago, the analysis of a high number of complex spectra was performed largely manually and therefore represented a limiting step in hit generation campaigns. Read More
