Pharmaceuticals

Within the realm of pharmaceutical research and development, analytical data from NMR, LCMS and other techniques is bought to bear at many stages of the process.

At the hit identification stage, ligand or protein based screening techniques with an NMR readout are used, as are MS based studies such as Affinity MS. As hits are expanded and progress to leads and candidates, synthetic chemistry kicks in, and there is a need for structural studies and purity checks. There is also a need to find ways to efficiently purify compounds. Particularly as compounds progress there is a need to understand and optimize chemical reactions, and metabolism and pharmacokinetic studies are needed to assess the fate of compounds or determine their effects on the body. When a compound is finally manufactured and marketed, we need to ensure its quality. All of these areas and others besides can be impacted by Mnova, its specialized plugins and the Mgears automation engine. Read on to learn more about how Mnova can assist in the pharma industry.