BiologicsHOS

BiologicsHOS for rapid assessment of quality and processes for Biologics therapeutics

BiologicsHOS (High Order Structure) is a suite of software tools designed to assist with the analysis of the NMR spectra of biotherapeutics. 2D NMR spectra of reference samples are compared with that of each test sample using a fingerprinting, or spectral similarity determination.

BiologicsHOS

Highlights

PCA analysis of filgrastim spectra
  • Designed to assist with the analysis of the NMR spectra of biotherapeutics
  • 2D NMR spectra of reference samples are compared with that of each test sample using a fingerprinting, or spectral similarity determination
  • We offer three published and accepted methods that can be used:

    • PCA – unsupervised chemometrics
    • ECHOS – simple representation of spectral differences
    • CCSD – number that represents the shifts in peak positions

Details may also be found by visiting Bruker Biospin

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