Mnova Gears – Chrom QC

Automated workflow for high throughput quality control using LC/GC-MS

Compound quality control can be challenging and time consuming when manual input for processing or result interpretation is needed. If you are an organic chemist, medicinal chemist, formulation scientist, or a quality specialist and want to analyze your compound libraries to assert compound identity and assess purity, Chrom QC is your best ally. This automation tool will run end-to-end QC workflows for you and deliver decision-enabling reports with all the results you’ll need.

Chrom QC runs on the Gears automation engine, which means that any LC/GC-MS format can be handled independently from the instrument software packages. Data is automatically retrieved from your directories (in batches or real time), matched to the corresponding molecular structures, formulae, masses, etc., and analyzed to confirm compound identity and determine purities. Custom csv, html, mnova, and PDF reports can also be automatically generated, and results can be sent directly to your database! Even better, all of this can be achieved with only minimal setup effort!

Chrom QC


  • Quality control all your compounds using one software package that supports all the major proprietary LC-MS data formats – make your quality control independent of the devices used!
  • Streamline your lot and batch release programs by automating data processing, analysis, and report generation
  • High-quality data in a timely manner to enhance your lab productivity
  • Effective result visualization with possible manual review
  • Save your compound results in your Mnova databases on-the-fly


Chrom QC: Installation

product_icon_download 1. Download

Download the latest version of Mnova Gears – Chrom QC

product_icon_download 2. Download 

Download the patch for Mnova Gears to ensure compatibility with Mgears 2.5

product_icon_install 3. Drag&Drop

Drag and drop these two files in Mnova. Follow instructions to complete the installation.


Chrom QC


  • Support to the majority of LC/GC-MS data formats
  • Automatic detection and matching of input data files with provided information
  • Flexible peak identification methods using molecular structures, formulae and masses, or peak size
  • Possible extraction of multiple traces for purity and concentration calculations
  • Automated reporting with customization options and use of design templates (html, mnova, PDF, csv)
  • Color-coded plate view to enable review-by-exception of the results
  • Manual peak selection tool for result correction
  • Automatic result archiving and databasing

More Automation

Purification Workflow

Looking for an enterprise-level solution for improving your purification and data management procedures? Check the Best Method and Fraction Analysis bricks that also run in full automation, and learn more about our automated databasing solution with Mgears. You have the complete flexibility to combine and adapt these solutions to your standard procedures to reap even more benefits for your organization.

Contact us for more information.

Academic, Government & Industrial


Who should be using Chrom QC?

Organic chemists, analysts, QC experts, and researchers using quantitative chromatographic methods for quality control, concentration/purity determination, or monitoring/optimization of reactions in one of the following markets and applications:

  • Pharmaceutical/Drug development industry
  • Food & Beverage industries
  • Personal care and Cosmetics
  • Fine chemical synthesis industries
  • Polymer industries
  • Academic research laboratories
  • Contract Research Organizations (CROs)

  • Quality control of synthesized or acquired compounds prior to registration
  • Quality control of compound collections prior to use in biological assays
  • Quality control of finished compounds prior release to the market (drugs, food additives, preservatives, etc.)
  • Quality control for formulation optimization and definition of storage recommendations