Mnova Gears – Fraction Analysis

Automated evaluation of collected elution fractions for decision making

To pool or not to pool? This may be a tricky question when more than one fraction has been collected for your sample during preparative chromatography.

Fraction Analysis will help you answer it quickly by automating the analysis of fractions and suggesting the most appropriate action to take. The tool will evaluate the number and size of peaks present in each fraction, match and assign your target peak, calculate its purity, then score and report the results automatically. After Fraction Analysis, you will be able to quickly review the results dashboard and pass the selected fraction to downstream quality control processes.

Software Solution for Chemical Reaction Optimization

Fraction Analysis


  • Huge time savings on spectral data analysis and preparation of professional-looking reports with the results
  • Reduce the risk of pooling a pure eluate fraction with a poor-quality one
  • Bring insight into the results and decide whether to stick to the suggested action or manually override it

Fraction Analysis


  • Automated data ingestion, processing, analysis, and report generation
  • Powerful scoring based on peak number, size, and target mass purity
  • Flexible analysis options
  • Color coded dashboards and tables with analysis results
  • Automatic, data-driven suggestion for subsequent action (to keep and QC, or dispose of or review the elution fraction)
  • Possibility to override the automatically generated results
  • Summary CSV output with results that can be used as input files for the next-stage analysis

More Automation

Purification Workflow

Looking for an enterprise-level solution for improving your purification and data management procedures? Check the Best Method and Quality Control bricks that also run in full automation, and learn more about our automated databasing solution with Mgears. You have the complete flexibility to combine and adapt these solutions to your standard procedures to reap even more benefits for your organization.

Contact us for more information.

Academic, Government & Industrial


Who should be using Fraction Analysis?

Organic chemists, analysts, QC experts, and researchers using quantitative chromatographic methods for quality control, concentration/purity determination, or monitoring/optimization of reactions in one of the following markets and applications:

  • Pharmaceutical/Drug development industry
  • Food & Beverage industries
  • Personal care and Cosmetics
  • Fine chemical synthesis industries
  • Polymer industries
  • Academic research laboratories
  • Contract Research Organizations (CROs) offering purification services

  • Compound purification for subsequent use in studies or commercialization
  • Isolation of unknown impurities in finished products, natural products, or in the environment for structural disclosure, study, etc.
  • Chiral separation to remove unwanted enantiomers obtained during organic synthesis