Analysis for the determination of a biologic drug’s higher order structure
Designed for the NMR analysis of biotherapeutics, like monoclonal antibodies. 2D NMR spectra of reference samples are compared with that of each test sample using a fingerprinting, or spectral similarity determination.
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HOS evaluation of medium to high molecular weight species.
Quality Assessment of Biologic drugs using 2D NMR spectral data.
Includes all the “Advanced Chemometrics” capabilities and 1D Profile, CSSD and ECHOS, PCA, PLS and SIMCA.
Signal processing such as compressed sensing, denoising, data alignment, and 2D cross-peak analysis.
Matrix evaluations of all spectra to compare intra- and inter-class samples.
Full automation capabilities that allow the saving and reuse of analysis methods.
Mnova BioHOS – NIST mAb data
Data from the NISTaMb study and reference material are available here
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