Mnova Screen is a simple, efficient tool with flexible analysis and reporting features, trusted by top pharmaceutical companies. It handles data from various screening experiments, including 1H or 19F, single compounds or mixtures, with or without reference spectra, and multiple spectra types.
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The latest Screen plugin update with Mnova 15.1 includes:
Considers the use of STD, wLOGSY, T1rho, and CPMG experiments.
Uses pattern recognition algorithms to analyze and map your experimental data.
Uses deconvolution to effectively pick peaks, even for weak signals.
Includes a results viewer for detailed result inspection of the analysis performed.
Results can be exported in various formats for easy handling in other software packages.
Includes ´Mix Design´, a tool that assists in designing optimized mixtures from compound libraries.
Several groups in Novartis use NMR binding assays to find and validate hits during the early stages of drug discovery. They use ligand-observed NMR experiments such as STD, T1ρ, and CPMG to identify library compounds that interact with a target protein.
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