A homodecoupled diffusion experiment for the analysis of complex mixtures by NMR
| Title: | A homodecoupled diffusion experiment for the analysis of complex mixtures by NMR |
| Authors: | J.C. Cobas, M. Martín-Pastor |
| Date: | 2004/08/04 |
| Reference: | J. Magn. Reson, 2004, 171, 20-24 |
| DOI: | http://dx.doi.org/10.1016/j.jmr.2004.07.016> |
Diffusion ordered spectroscopy (DOSY) relies on differences in translation diffusion as a means to separate components in a solution mixture. However, the analysis of spectra of mixtures can be problematic because spectral overlap. It is the aim of this article to propose a pulse sequence and processing method that leads to a complete 2D homodecoupled-DOSY experiment. This experiment offers several advantages that could extend the range of applications to more complex mixtures by achieving important improvements in both signal dispersion and sensitivity.
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