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Analysis and selection of the optimal separation method

Chrom Best Method is a vendor-agnostic tool that seamlessly screens and compares multiple chromatographic methods, then suggests the one more likely to yield a pure compound. Chrom Best Method automates LC-MS data processing, target and impurity identification, method scoring, and report generation, providing quick, smart, and robust answers while still allowing for full review and overriding of results to accommodate users’ needs.

Software Solution for Chemical Reaction Optimization

Chrom Best Method

Benefits

Effective, vendor-neutral analysis and comparison of your LC-MS data from different instruments in one software package.

Seamless evaluation of several methods for many targets in a single run, which accommodates HT experimentation.

Meaningful method scores based on your criteria, preferences, and operational requirements.

Substantial reduction in the time spent on manual analysis and creation of reports.

Effective result visualization and interpretation, enabling quick and confident decision making.

Chrom Best Method

Features

  • Automated data preparation, analysis, and reporting of results
  • Comprehensive method scoring that generates meaningful results
  • Powerful target peak assignment options and detection of impurities
  • Multiple ways to provide target information (using a structure, dataset file name, mapping file, or parameters)
  • Flexible ion matching and analysis options that fit multiple-use cases
  • Optimized algorithm for chiral screening
  • Possibility to screen methods on different targets in a single run
  • Manual review by exception of scoring and ability to override results
Gears Chrom Best Method
Latest Chrom Best Method news
scoring-chiral-compounds-with-Chrom-Best-Method

Scoring of LC separation procedures for a chiral compound using Mgears Chrom Best Method

In this application note, Prof. Rafael Cela and Dr. Leticia Pérez-Mayán outline the use of Chrom Best Method for evaluating LC separation of diniconazol, showcasing its effectiveness in meeting the analytical demands for a successful chiral separation.

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Scoring Application Note

Scoring of LC separation procedures for ezetimibe and its degradants

In this application note, Prof. Rafael Cela, showcases the selection of LC procedures using Mgears Chrom Best Method and highlights how automation streamlines the screening process and helps in analysis, reporting and decision…

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Webinar | Automation in a purification lab at AstraZeneca

Automating the processing of analytical data for multiple drug discovery applications.

Join us for an insightful session where scientists and IT professionals from AstraZeneca come together to explore the complexities of managing analytical data within a purification lab setting.

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Help & Resources

Guides & Manuals

Chrom Best Method Starting Guide Mnova Gears Manual

Videos

Webinar | Automation in a purification lab at AstraZeneca

Resources

Scoring of LC separation procedures for a chiral compound using Mgears Chrom Best Method Scoring of LC separation procedures for ezetimibe and its degradants Introducing the Mnova Purification Suite: your solution for streamlined chromatography purifications! Managing data workflows in a purification laboratory Evaluating Chromatographic Methods: Scoring Criteria and Considerations
Chrom Best Method

Related Applications

Academic, Government & Industrial

Target Audience

Analytical Chemists
Separation Scientists
Other Mnova Solutions

Related Products

The project is supported by Red.es and co-financed with FEDER funds within the framework of the Pluriregional Operational Program of Spain (POPE) 2014-2020. (El proyecto impulsado por Red.es está cofinanciado con fondos FEDER en el marco del Programa Operativo Plurirregional de España (POPE) 2014-2020). 

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