The automatic analysis of NMR data has been a much-desired endeavour for the last six decades, as it is the case with any other analytical technique.
Since the first experiments on the detection of nuclear resonance signals, NMR spectroscopy has been successfully used as quantitative technique applied to several kind of matrixes.
Multiple myeloma (MM) is a malignancy of plasma cells characterized by multifocal osteolytic bone lesions. Macroscopic and genetic heterogeneity has been documented within MM lesions. Understanding the bases of such heterogeneity may unveil relevant features of MM pathobiology.
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The NMR Spectrometer: I will have to be a little vague at times in this section, as specifics will depend on your spectrometer vendor and age.
In this section I will consider just the basics of data processing before describing how to determine the purity.