It is necessary to show that the active content in the dosage form of drugs is within a certain narrow range of the label claim.
Spectroscopic methods – of which nuclear magnetic resonance (NMR) is one of the most vital players – have almost entirely replaced those old “wet chemistry”-based approaches and the art has become a science.
Checking for any inconsistencies in your results:
The alert set-up is an important SMA feature that can be configured to give you feed-back when it does not find the multiplets you specify and expect. We call these “Alerts”.
From the “Experiment” panel, you can configure SMA in terms of the alerts it may show.
The way the spectral integrals are converted into meaningful, quantitative information in SMA is manually determined by you using the Formula Editor located in the “Experiment” panel. You have full control over the calculation method and you define how quantification is performed for a constituent by entering basic maths functions in the formula editor.
Customize your own mixtures analysis:
If you were happy testing the provided worked example (Brucine with spiked ether) explained in our “getting started” guide then it is your turn to create your own library of compounds and experiments.