Pseudo-2D NMR provides a means of acquiring broadband homonuclear decoupled spectra useful for structural characterization of complex molecules.
Several groups in Novartis use NMR binding assays to find and validate hits during the early stages of drug discovery. They use ligand-observed NMR experiments such as STD, T1ρ, and CPMG to identify library compounds that interact with a target protein.
Computer-assisted methods development (CAMD) of LC (liquid chromatography) separations comprises the strategies, methodologies, and software that can be used for more effective and efficient development of separations needed in the analytical chromatography laboratory.